Acral Calcified Vascular Leiomyoma: Report of 3 Cases and Literature Review.

Department of Pathology, Hospital Clínico de Santiago de Compostela, Santiago, Spain. Department of Forensic Sciences and Pathology, University of Santiago de Compostela, Santiago, Spain. Department of Dermatology, Hospital Clínico de Santiago de Compostela, Santiago, Spain ; and. Department of Pathology, Hospital Universitari General de Catalunya, Grupo Quironsalud and Universitat Internacional de Catalunya, Barcelona, Spain.

The American Journal of dermatopathology. 2021;(10):732-735

Abstract

Angioleiomyomas are benign neoplasms, which usually present as solitary, slow-growing nodules on the skin of lower extremities, but acral location on the hands or feet is unusual. Yet, microscopically, they may show many histopathological variants, focal calcification is uncommon. Extensive calcification masquerading the real nature of the tumor has been rarely reported, the term acral calcified leiomyoma having been proposed for this entity. This change is more often in distal locations and has been interpreted as degenerative in nature, probably related to repetitive minor trauma. We report 3 examples of this unusual condition on the feet of 2 male and one female subjects (aged, 68, 69, and 80 years) and make a review of the 31 cases available in the literature. Two of our cases are associated with highly uncommon features, such as transepidermal calcium elimination and concomitant calcaneal spur.

Methodological quality

Publication Type : Case Reports ; Review

Metadata